Light-driven self-disinfecting textiles functionalized by PCN-224 and Ag nanoparticles.

Area of Science:

• Materials Science
• Biotechnology
• Textile Engineering

Background:

• Healthcare-associated infections are a significant concern.
• Development of antimicrobial textiles is crucial for infection control.

Purpose of the Study:

• To create a self-disinfecting textile with combined photodynamic and photothermal antibacterial properties.
• To investigate the synergistic effects of Metal-organic frameworks and silver nanoparticles for enhanced disinfection.

Main Methods:

• In situ growth of Porphyrinic Metal-organic frameworks (PCN-224) and silver nanoparticles (Ag NPs) on knitted cotton textile (KCT).
• Evaluation of antibacterial efficacy against E. coli and S. aureus under light irradiation.
• Assessment of durability through multiple washing cycles.
• Mechanism studies involving singlet oxygen generation and photothermal effects.

Main Results:

• The developed textile demonstrated rapid photodynamic and durable bacteriostatic effects.
• Achieved 6 and 4.49 log unit inactivation of E. coli and S. aureus, respectively, within 30 minutes.
• Maintained significant antibacterial activity (6 log unit inactivation) after ten washes.
• Synergistic action of singlet oxygen and heat enhanced bacterial inactivation efficiency.

Conclusions:

• The synergistic self-disinfecting cotton textile shows significant potential for preventing microbial infections and transmissions in healthcare settings.
• The combination of photodynamic and photothermal properties offers a robust approach to antimicrobial textile development.
• The textile's durability ensures long-term effectiveness in infection control applications.