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Related Concept Videos

Drugs Affecting GI Tract Motility: Other Laxatives01:20

Drugs Affecting GI Tract Motility: Other Laxatives

Laxatives are primarily used to alleviate constipation, a common gastrointestinal disorder characterized by infrequent bowel movements and difficulty passing stools. They work by various mechanisms to increase the volume or frequency of bowel movements. The primary modes of action of laxatives include increasing stool bulk, softening the stool, stimulating intestinal motility, and osmotically drawing water into the intestines.
Osmotic or saline laxatives, like magnesium hydroxide or milk of...
Drugs Affecting GI Tract Motility: Adsorbents as Antidiarrheal Agents01:20

Drugs Affecting GI Tract Motility: Adsorbents as Antidiarrheal Agents

Diarrhea is characterized by the occurrence of frequent, watery bowel movements. Various factors can trigger diarrhea, including viral or bacterial infections, foodborne illnesses, side effects from certain medications, and underlying digestive disorders. If not adequately managed, diarrhea can lead to complications such as dehydration, electrolyte imbalances, and nutrient deficiencies. Severe diarrhea can lead to significant weight loss, malnutrition, and weakened immune function.
Adsorbents...
Drugs Affecting GI Tract Motility: Antimicrobials as Antidiarrheal Agents01:18

Drugs Affecting GI Tract Motility: Antimicrobials as Antidiarrheal Agents

Acute diarrhea, a common gastrointestinal disturbance, is characterized by the rapid evacuation of fluid stools, leading to an excessive weight in fluid. This condition typically arises from disorders affecting intestinal water and electrolyte transport. It can be triggered by an increased osmotic load within the intestine, excessive secretion of electrolytes and water, mucosal exudation of protein and fluid, or altered intestinal motility. The primary risks of acute diarrhea are dehydration...
Drugs for Treatment of Diarrhea-Predominant IBS01:17

Drugs for Treatment of Diarrhea-Predominant IBS

Diarrhea-predominant irritable bowel syndrome (IBS-D) is a subtype of IBS characterized primarily by frequent, loose, or watery stools, abdominal pain, and abdominal discomfort. Therapeutic approaches to managing IBS-D include dietary changes, stress management techniques, and pharmaceutical interventions.
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
Bacterial Gastroenteritis01:18

Bacterial Gastroenteritis

Bacterial gastroenteritis, characterized by diarrhea, abdominal cramps, and vomiting, is often caused by ingestion of contaminated food or water and is frequently associated with pathogenic Escherichia coli strains. These microbes exploit two principal mechanisms to inflict disease.Shiga toxin–producing E. coli, also referred to as STEC—notably O157:H7—release Shiga toxins that target ribosomes, blocking protein synthesis. The B subunit of the toxin binds the host glycolipid receptor...
Giardiasis01:12

Giardiasis

Giardiasis is a globally prevalent intestinal infection caused by the protozoan parasite Giardia duodenalis (also known as G. lamblia or G. intestinalis). This flagellated protozoan is the most frequently identified intestinal parasite in the United States and worldwide. Transmission primarily occurs via the fecal-oral route, with infection arising from ingestion of water or food contaminated with cysts. Individuals in low-resource settings, international travelers, outdoor enthusiasts, daycare...

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Related Experiment Video

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A High-throughput Platform for the Screening of Salmonella spp./Shigella spp.
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Published on: November 7, 2018

Update on traveler's diarrhea.

W B Strum1

  • 1Division of Gastroenterology, Scripps Clinic, La Jolla, CA 92037.

Postgraduate Medicine
|July 1, 1988
PubMed
Summary

Prevent traveler's diarrhea by choosing safe foods and water. While medications can help severe cases, prevention through education and hygiene is key for healthy travel.

Area of Science:

  • Infectious Diseases
  • Public Health
  • Travel Medicine

Background:

  • Traveler's diarrhea (TD) is a common gastrointestinal illness affecting many individuals traveling to high-risk regions globally.
  • Effective prevention strategies are crucial for mitigating the impact of this prevalent travel-related health issue.

Purpose of the Study:

  • To outline the primary preventive measures for traveler's diarrhea.
  • To discuss the role of prophylactic medications and treatment options for TD.
  • To emphasize the importance of patient education and safe practices in managing TD.

Main Methods:

  • Review of established guidelines and recommendations for traveler's diarrhea prevention.
  • Emphasis on patient education regarding safe food and water consumption.

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Ginger Moxibustion, A Non-pharmacological Treatment, for Diarrhea in Patients with Chronic Obstructive Pulmonary Disease

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  • Discussion of pharmacological interventions, including prophylactic and therapeutic agents.
  • Main Results:

    • Patient education on avoiding high-risk foods and ensuring water purity (e.g., boiling) is the most critical preventive measure.
    • Mild TD cases typically require only fluid and electrolyte replacement, potentially with an antidiarrheal agent.
    • Moderate to severe TD cases may benefit from antimicrobial therapy.

    Conclusions:

    • Caution, common sense, and adherence to dietary and hygienic practices are the primary defenses against traveler's diarrhea.
    • Prophylactic medications should be used judiciously.
    • Long-term solutions involve improved global sanitation and personal hygiene, though immediate practical measures are essential.