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Updated: Nov 8, 2025

A Pipeline to Investigate the Structures and Signaling Pathways of Sphingosine 1-Phosphate Receptors
Published on: June 8, 2022
An introduction to plant sphingolipids and a review of recent advances in understanding their metabolism and function
Daniel V Lynch1, Teresa M Dunn2
1Department of Biology, Williams College, Williamstown, MA 01267, USA.
Abstract:
Sphingolipids are ubiquitous constituents of eukaryotic cells, and have been intensively investigated in mammals and yeast for decades. Aspects of sphingolipid biochemistry in plants have been explored only recently. To date, progress has been made in determining the structure and occurrence of sphingolipids in plant tissues; in characterizing the enzymatic steps involved in production and turnover of sphingolipids (and, in some cases, the genes encoding the relevant enzymes); and in identifying a variety of biological functions for sphingolipids in plants. Given that these efforts are far from complete and much remains to be learned, this review represents a status report on the burgeoning field of plant sphingolipid biochemistry. Contents Summary 677 I. Introduction 678 II. Plant sphingolipid structure 678 III. Sphingolipid metabolism in plants 683 IV. Sphingolipid functions in plants 693 V. Conclusions 696 Acknowledgements 696 References 696.
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