Cardiovascular Complications in Major 21st Century Viral Epidemics and Pandemics: an Insight into COVID-19

Muzna Hussain1, Patrick Collier1, Rohit Moudgil1

  • 1Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, Ohio, USA.

Insights

Major 21st-century epidemics, including COVID-19, can lead to cardiovascular complications, particularly in individuals with pre-existing heart conditions. This review examines these infectious disease outbreaks and their varied cardiovascular effects.

Area of Science:

  • Infectious Diseases
  • Cardiology
  • Epidemiology

Background:

  • Acute infections are known to precipitate cardiovascular (CV) complications.
  • Individuals with underlying cardiac conditions are particularly vulnerable to these CV effects.
  • The 21st century has witnessed several significant epidemics and pandemics.

Purpose of the Study:

  • To review major epidemics and pandemics of the 21st century.
  • To discuss the spectrum of associated cardiovascular disease (CVD) complications.
  • To highlight the novelty of CV effects observed in the COVID-19 pandemic.

Main Methods:

  • Literature review of major 21st-century epidemics and pandemics.
  • Analysis of reported cardiovascular complications associated with these outbreaks.
  • Focus on the specific cardiovascular manifestations linked to coronavirus disease 2019 (COVID-19).

Main Results:

  • Significant variation exists in the rates and types of CVD complications across different epidemics.
  • COVID-19 has emerged as a major global health crisis with substantial human and economic impact.
  • Emerging cardiovascular effects associated with COVID-19 represent a novel clinical entity.

Conclusions:

  • Infectious disease outbreaks in the 21st century pose a significant threat of cardiovascular complications.
  • Understanding the diverse CVD profiles associated with pandemics is crucial for clinical management.
  • Further research into the novel cardiovascular sequelae of COVID-19 is warranted.

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