Related Experiment Video
Updated: Nov 8, 2025

Author Spotlight: Expanding Interventional Pulmonology Research with Robotic-Assisted Bronchoscopy
Published on: July 19, 2024
Subcutaneous emphysema after intralesional cryotherapy: An unusual complication
Tuğba Falay Gür1, Sevil Savaş Erdoğan1, Cüneyt Kara2
1Department of Dermatology, University of Health Sciences, Sultan 2. Abdulhamid Han Training and Research Hospital, Istanbul, Turkey.
Background:
Intralesional cryotherapy (ILC) is a safe and well tolerated by the patient. Subcutaneous emphysema (SE) cases after spray and contact cryotherapy have been described; however, this complication has not been previously reported after ILC.
Aim:
Our aim is to discuss the possible causes of SE development after ILC.
Method:
We present a young patient that developed SE after ILC applying by insertion of an open-ended needle to the tip of the cryotherapy gun.
Results:
The development of SE following ILC may have been caused by inward clefting from the ear hole, the usage of an open-ended needle and a lack of safety system.
Conclusion:
It will be safer to apply special methods involving the usage of sealed distal type to prevent SE development.
Related Concept Videos
Pneumothorax-II
Clinical Manifestations:
Clinical Applications of Epidermal Stem Cells

