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Related Experiment Videos

Standardization of different spirometers.

B A Ali1, Y M Abro, N H Javed

  • 1Department of Physiology, College of Medicine and Medical Sciences, King Faisal University, Dammam, Saudi Arabia.

Respiration; International Review of Thoracic Diseases
|January 1, 1988
PubMed
Summary

Different spirometers used for lung function testing yield varying results, indicating they are not interchangeable. Biological standardization is crucial for accurate human testing with devices like the Vitalograph and Harvard spirometers.

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Area of Science:

  • Pulmonary Function Testing
  • Medical Device Evaluation
  • Respiratory Diagnostics

Background:

  • Spirometry is essential for diagnosing and monitoring respiratory diseases.
  • Standardization of spirometer performance is critical for reliable clinical data.
  • The American Thoracic Society (ATS) provides guidelines for spirometer requirements.

Purpose of the Study:

  • To compare the performance of different spirometers used in human testing.
  • To assess the interchangeability of results from ATS-compliant spirometers.
  • To evaluate three specific spirometry devices: Harvard, Vitalograph, and Gould.

Main Methods:

  • Comparison of a water-sealed spirometer (Harvard), a dry bellows wedge spirometer (Vitalograph), and a computerized pneumotachograph (Gould).

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  • All devices met American Thoracic Society (ATS) recommendations.
  • Measurement of Forced Vital Capacity (FVC), FEV1, FEF 25-75%, and FEV1% in 40 healthy volunteers.

    • Main Results:

    • Vitalograph spirometer showed significantly higher FVC, FEV1, and FEV1% values compared to the Harvard spirometer.
    • Vitalograph results were closely similar to those obtained from the Gould computerized pneumotachograph.
    • No significant differences were noted for FEF 25-75% across the devices.

    Conclusions:

    • Results from different spirometers, even those meeting ATS standards, are not interchangeable.
    • Biological standardization of spirometers against each other is essential for consistent and accurate pulmonary function testing.
    • Clinical decisions based on spirometry should consider the specific device used.