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Locust as an in Vivo Model.
Ruqaiyyah Siddiqui1, Jibran Sualeh Muhammad2, Naveed Ahmed Khan2
1College of Arts and Sciences, American University of Sharjah, Sharjah 26666, United Arab Emirates.
ACS Chemical Neuroscience
|April 20, 2021
Summary
Locusts are valuable in vivo models for studying brain development and function. Their genomic data and handling ease enable research into brain formation and adaptation in diverse environments.
Area of Science:
- Neuroscience
- Developmental Biology
- Genomics
Background:
- Advances in locust genome sequencing are now available.
- High-throughput genomics technologies offer new research avenues.
- Locusts possess unique traits making them suitable for biological studies.
Purpose of the Study:
- To highlight locusts as a model organism for studying embryonic development.
- To explore brain formation, functional adaptations, and neuropathogenesis in locusts.
- To investigate how environmental niches influence locust neurodevelopment.
Main Methods:
- Utilizing newly available locust genome sequence information.
- Employing high-throughput genomics capabilities.
- Applying novel approaches for genetic traceability.
- Leveraging the large size of locusts for experimental handling.
Main Results:
- Locusts serve as an effective in vivo tool for neurodevelopmental research.
- The combination of genomic data and advanced techniques facilitates detailed study.
- Ease of handling and genetic traceability enhance experimental efficiency.
Conclusions:
- Locusts are a powerful model for in vivo studies of brain development.
- Their utility extends to understanding functional adaptations and neuropathogenesis.
- Environmental influences on neurodevelopment can be effectively studied in locusts.

