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Updated: Nov 8, 2025

Myocardial Infarction in Neonatal Mice, A Model of Cardiac Regeneration
Published on: May 24, 2016
Neonatal Myocardial Infarction in Association With Gestational Diabetes
Safwat Aly1, Julien Aguet2, Andreea Dragulescu1
1Department of Pediatrics, Division of Cardiology, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.
Abstract:
Fetal and neonatal hypertrophic cardiomyopathy is a complication of gestational diabetes and usually follows a benign course. In this report, we present a rare case of a newborn of a diabetic mother with severe ventricular hypertrophy who developed myocardial infarction confirmed by elevated cardiac enzymes, electrocardiographic changes, and subendocardial ischemia on cardiac magnetic resonance imaging. Follow-up revealed complete functional myocardial recovery with normalisation of ventricular systolic and diastolic functions on serial echocardiograms.
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