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Glaucoma: Overview

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

Open Angle Glaucoma: Treatment

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...

Angle Closure Glaucoma: Treatment

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

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Related Experiment Video

Updated: Nov 8, 2025

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Published on: February 15, 2022

Changes in corneal thickness after vitrectomy-Implications for glaucoma practice.

Lisika Gawas¹, Aparna Rao¹

¹Glaucoma Services, LV Prasad Eye Institute, Bhubaneswar, India.

|April 21, 2021

Summary

This summary is machine-generated.

Younger patients under 25 show increased central corneal thickness (CCT) changes after vitrectomy, indicating a higher susceptibility to corneal remodeling. This finding is crucial for understanding post-vitrectomy ocular health in this demographic.

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Area of Science:

Ophthalmology
Corneal Science
Glaucoma Research

Background:

Vitrectomy is a common surgical procedure for various ocular conditions.
Secondary glaucoma can occur after vitrectomy, necessitating careful monitoring.
Changes in central corneal thickness (CCT) post-vitrectomy are not fully understood.

Purpose of the Study:

To evaluate changes in central corneal thickness (CCT) after vitrectomy.
To identify factors influencing CCT alterations following the procedure.

Main Methods:

Retrospective analysis of patients undergoing vitrectomy between 2013 and 2020.
Comparison of CCT between affected eyes (post-vitrectomy with elevated IOP) and control eyes.
Multivariate regression analysis to correlate CCT with age, surgical details, and lens status.

Main Results:

Affected eyes showed significantly higher CCT than control eyes (p<0.0001).
Eyes presenting at age <25 years exhibited greater CCT differences (ΔCCT) compared to older groups (p<0.0001).
Younger age (<25 years) was a significant predictor of CCT changes in affected eyes (R2 = 28.3%).

Conclusions:

Patients under 25 years old are more susceptible to corneal remodeling and CCT changes post-vitrectomy.
Age is a significant factor influencing corneal biomechanical alterations after vitrectomy.
Further research may elucidate the mechanisms behind age-related CCT changes post-vitrectomy.