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Updated: Aug 17, 2026

Electrolytic Inferior Vena Cava Model (EIM) of Venous Thrombosis
Published on: July 12, 2011
Congenital deficiency of plasminogen and its relationship to venous thrombosis
V Hach-Wunderle1, I Scharrer, R Lottenberg
1Department of Internal Medicine, University Hospital, Frankfurt/Main, FRG.
Abstract:
In a patient with deep venous thrombosis, plasma concentrations of coagulant and inhibitor proteins were normal except for moderate deficiency of plasminogen. Family studies revealed a similar deficiency in the mother and sister of the propositus. Evaluation of purified plasminogen demonstrated that it functioned normally. The patient represents our only example of plasminogen deficiency in 435 German individuals evaluated with a history of thromboembolism.
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