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Pyomyositis and Infectious Myositis: A Comprehensive, Single-Center Retrospective Study
Christopher Radcliffe1, Savanah Gisriel2, Yu Si Niu1
1Yale University School of Medicine, New Haven, Connecticut, USA.
Open Forum Infectious Diseases
|April 22, 2021
Summary
Pyomyositis and infectious myositis are bacterial muscle infections. Management often requires antibiotics and drainage procedures, with Gram-positive bacteria being the most common cause.
Area of Science:
- Infectious Diseases
- Musculoskeletal Infections
Background:
- Pyomyositis is a bacterial skeletal muscle infection often causing abscesses.
- Infectious myositis is a related but distinct condition.
- Recent shifts in the epidemiology of these infections are noted.
Purpose of the Study:
- To characterize pyomyositis and infectious myositis.
- To analyze patient demographics, pathogens, symptoms, and treatment outcomes.
Main Methods:
- Retrospective study at a tertiary care institution.
- Inclusion of 43 cases of pyomyositis and 18 cases of infectious myositis.
- Data collection from January 2012 to May 2020.
Main Results:
- Mean patient age 48 years, 66% male; 33% had diabetes, 16% other comorbidities.
- Staphylococcal species caused 46% of infections; common symptoms were muscle pain (95%) and fever (49%).
- 84% treatment success rate; 28% required multiple drainage procedures.
Conclusions:
- Gram-positive bacteria are the primary cause of these infections.
- Management frequently involves antibiotics and surgical drainage.
- Prospective studies are needed to optimize treatment strategies.
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