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Updated: Jun 18, 2026

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Published on: December 9, 2022
Radiofrequency ablation for markedly incompetent perforators versus compression therapy in the management of
Mohamed Shukri Abdelgawad1, Amr M El-Shafei1, Hesham A Sharaf El-Din1
1Department of Vascular and Endovascular Surgery, Mansoura University Hospitals, Mansoura University, Mansoura, Egypt.
Background:
Venus ulcers developed mainly due to reflux of incompetent venous valves in perforating veins.
Patients And Methods:
In this randomized controlled trial, 119 patients recruited over two years, with post-phelebtic venous leg ulcers, were randomly assigned into one of two groups: either to receive radiofrequency ablation of markedly incompetent perforators (Group A, n = 62 patients) or to receive conventional compression therapy (Group B, n = 57 patients). Follow-up duration required for ulcer healing continued for 24 months post randomization.
Results:
Statistically significant shorter time to healing (ulcer complete healing or satisfactory clinical improvement) between both groups (56 patients, 90.3% of cases in Group A versus 44 patients 77.2% of cases in Group B) over the follow-up period of 24 months was attained (p = 0.001). Also, significantly different ulcer recurrence was recorded between both groups, 8 patients (12.9%) in Group A versus 19 patients (33.3%) in Group B (p = 0.004).
Conclusion:
In absence of deep venous obstruction, the monopolar radiofrequency ablation for incompetent perforators is a feasible and effective method that surpasses the traditional compression protocol for incompetent perforator-induced venous ulcers in terms of time required for healing even in the presence of unresolved deep venous valvular reflux.
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