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Epidemiology, virology and clinical aspects of hantavirus infections: an overview

Sima Singh1, Arshid Numan2, Dinesh Sharma3

  • 1Department of Pharmacy, University Institute of Pharma Sciences, Chandigarh University, Gharuan, Mohali, India.

International Journal of Environmental Health Research
|April 22, 2021
PubMed

Insights

Hantavirus infections, causing hemorrhagic renal syndrome (HFRS) and hantavirus cardiopulmonary syndrome (HCPS), pose a growing global health threat. Effective treatments and vaccines are lacking, emphasizing the need for public awareness and preparedness.

Area of Science:

  • * Infectious Diseases
  • * Virology
  • * Public Health

Background:

  • * The COVID-19 pandemic highlighted global unpreparedness for communicable diseases.
  • * Hantavirus infections represent a significant emerging public health concern.
  • * Hantavirus, a zoonotic pathogen, causes severe diseases like HFRS and HCPS.

Purpose of the Study:

  • * To review the epidemiology, virology, and clinical manifestations of Hantavirus.
  • * To discuss current management strategies for HFRS and HCPS.
  • * To enhance understanding of virus-host interactions for future outbreak preparedness.

Main Methods:

  • * Comprehensive literature review of Hantavirus epidemiology, virology, and clinical presentations.
  • * Analysis of existing management approaches for HFRS and HCPS.
  • * Synthesis of current knowledge on virus-host interactions.

Main Results:

  • * Hantavirus infections are a significant zoonotic threat with no current vaccines or effective treatments.
  • * HFRS and HCPS are the primary clinical syndromes associated with Hantavirus.
  • * Public awareness and precautionary measures are crucial for disease control.

Conclusions:

  • * Enhanced understanding of Hantavirus is critical for effective public health response.
  • * Further research into virus-host interactions may facilitate the development of treatments and vaccines.
  • * Proactive preparedness is essential to manage Hantavirus outbreaks in a changing global health landscape.

Keywords:
HCPSHFRSHantaviruscommunicable diseasesinfectious diseasezoonosis

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