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Quality of life and long-term outcomes after hospitalization for COVID-19: Protocol for a prospective cohort study

Regis Goulart Rosa1,2, Caroline Cabral Robinson1, Viviane Cordeiro Veiga2,3

  • 1Hospital Moinhos de Vento - Porto Alegre (RS), Brasil.

Revista Brasileira De Terapia Intensiva
|April 22, 2021
PubMed

Insights

Long COVID survivors face unknown long-term health effects. This study in Brazil tracks survivors for a year to identify factors impacting their quality of life and health outcomes post-COVID-19 hospitalization.

Area of Science:

  • Infectious Diseases
  • Public Health
  • Epidemiology

Background:

  • The long-term health consequences of COVID-19 remain largely unknown.
  • Hospitalized COVID-19 survivors are a vulnerable population requiring extended monitoring.
  • Understanding post-COVID-19 sequelae is crucial for public health strategies and patient care.

Purpose of the Study:

  • To assess health-related quality of life (HRQoL) and long-term outcomes in COVID-19 survivors hospitalized in Brazil.
  • To identify demographic, clinical, and treatment-related factors associated with HRQoL and outcomes.
  • To provide insights into the post-hospitalization recovery trajectory of COVID-19 patients.

Main Methods:

  • A multicenter prospective cohort study nested within five randomized clinical trials in Brazil.
  • Follow-up of adult COVID-19 survivors for 1 year via structured telephone interviews.
  • Primary outcome: 1-year HRQoL (EuroQol-5D-3L). Secondary outcomes: mortality, cardiovascular events, rehospitalization, functional status, dyspnea, mental health, and self-rated health.

Main Results:

  • Data collection and analysis are ongoing; specific results are pending.
  • The study is designed to identify significant associations between patient characteristics/illness factors and long-term outcomes.
  • Findings will elucidate the multifaceted recovery process following severe COVID-19.

Conclusions:

  • The study will provide critical data on the long-term impact of COVID-19 hospitalization.
  • Identifying risk and protective factors will inform clinical management and support for survivors.
  • Results will contribute to a better understanding of post-COVID-19 syndrome and guide future research and healthcare policies.
Abstract

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