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Synthesis and structure-activity relationships of new chiral spiro-β-lactams highly active against HIV-1 and

Nuno Guerreiro Alves1, Inês Bártolo2, Américo J S Alves1

  • 1University of Coimbra, Coimbra Chemistry Centre and Department of Chemistry, 3004-535, Coimbra, Portugal.

European Journal of Medicinal Chemistry
|April 22, 2021
PubMed

Keywords:
1,3-Dipolar cycloaddition2-ButynoatesAllenesAnti-HIV agentsAntiplasmodial agentsPhosphane-catalyzed [3+2] annulationsSpiro-3H-pyrazole-β-lactamsSpiro-penicillanatesSpirocyclic compoundsSpirocyclopentenyl-β-lactamsβ-Lactams

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