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Related Experiment Video

Updated: Nov 8, 2025

A Novel Digital Platform for a Monitored Home-based Cardiac Rehabilitation Program

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Targeting Sedentary Behavior in CKD: A Pilot and Feasibility Randomized Controlled Trial.

Kate Lyden^1,2, Robert Boucher³, Guo Wei^3,4

¹Department of Kinesiology, University of Massachusetts, Amherst, Massachusetts.

Clinical Journal of the American Society of Nephrology : CJASN

|April 23, 2021

Summary

Reducing sedentary behavior in chronic kidney disease (CKD) patients is feasible. However, the positive effects on sedentary and stepping durations were not sustained long-term in this study.

Keywords:

behavioral intervention chronic kidney disease sedentary behavior

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Area of Science:

Nephrology
Public Health
Exercise Science

Background:

Sedentary behavior is prevalent in patients with chronic kidney disease (CKD).
Reducing sedentary time is a potential strategy to improve health outcomes in CKD populations.

Purpose of the Study:

To test the feasibility of a "Sit Less, Interact, Move More" intervention to reduce sedentary behavior in CKD patients.
To assess the impact of the intervention on sedentary and stepping durations.

Main Methods:

A 24-week parallel-group randomized controlled trial was conducted with patients (stages 2-5 CKD).
The intervention group (n=54) received individualized plans targeting sedentary and stepping durations, monitored by accelerometry.
The control group (n=52) received national physical activity recommendations.

Main Results:

While the intervention group showed initial reductions in sedentary time and increases in stepping time, these changes attenuated by week 24.
Between-group differences in sedentary and stepping durations were not statistically significant at follow-up.
The intervention did significantly reduce body mass index and body fat percentage.

Conclusions:

Reducing sedentary behavior and increasing stepping duration in CKD patients is feasible.
The observed benefits on sedentary and stepping durations were not sustained throughout the 24-week study period.