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Adrenal Gland Disorders01:27

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Adrenal gland disorders manifest when the production of adrenal hormones deviates from the norm, resulting in either excessive or insufficient concentrations.
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A Novel Method: Super-selective Adrenal Venous Sampling
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Non-functioning adrenocortical carcinoma.

Bui-Van Lenh1,2, Nguyen Minh Duc2,3,4, Thieu-Thi Tra My2

  • 1Department of Radiology, Hanoi University Medical Hospital, Hanoi, Vietnam.

Radiology Case Reports
|April 23, 2021
PubMed
Summary

Adrenocortical carcinoma (ACC) is a rare cancer. This case report emphasizes how imaging and pathology are crucial for diagnosing non-functioning ACC and predicting patient outcomes.

Keywords:
Adrenal tumorAdrenocortical carcinomaRare neoplasm

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Area of Science:

  • Endocrinology
  • Oncology
  • Radiology

Background:

  • Adrenocortical carcinoma (ACC) is a rare adrenal cortex malignancy, presenting as functioning or non-functioning types.
  • Non-functioning ACC often lacks specific symptoms, making diagnosis challenging.

Observation:

  • A 32-year-old male patient presented with non-functioning ACC.
  • Radiological analysis revealed tumor size, density, washout, necrosis, hemorrhage, and calcification.
  • Histopathological examination provided Weiss score, resection surface details, Ki-67 index, and invasion status.

Findings:

  • The case highlights the diagnostic utility of imaging features like tumor characteristics.
  • Histopathology confirmed ACC and provided critical prognostic information through microscopic findings.
  • The importance of integrating radiological and pathological data for accurate diagnosis and prognosis is underscored.

Implications:

  • Accurate diagnosis of ACC relies on a combination of imaging and histopathology.
  • Radiological and pathological features serve as vital prognostic indicators for adrenocortical carcinoma.
  • This case emphasizes the need for thorough evaluation in suspected ACC cases, even with non-specific symptoms.