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Updated: Nov 8, 2025

Microfluidics in Assessing Platelet Function
Published on: November 8, 2024
A rare case of eptifibatide-induced thrombocytopenia
Khalil Kamar1, Kira MacDougall1, Mira Alsheikh1
1Department of Internal Medicine, Zucker School of Medicine at Hofstra/Northwell at Staten Island University Hospital, New York, NY, USA.
Abstract:
Eptifibatide is a glycoprotein (GP) IIb/IIIa receptor antagonist, used for the treatment of acute coronary syndrome with high-risk features or ongoing ischemia. Several case reports have described thrombocytopenia as a rare side effect of eptifibatide administration. The exact mechanism remains unclear but may be due to immune destruction of circulating platelets in the peripheral blood. We present the case of acute-onset severe thrombocytopenia in a 76-year-old female undergoing percutaneous coronary intervention.
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