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Updated: Nov 8, 2025
Systematic Assessment of Mammalian Skull Specimens for Dental and Temporomandibular Joint Pathology
Published on: August 22, 2022
An unusual case of tricho-dento-osseous syndrome
Abbas Haghighat1, Sobhan Pourarz2, Maryam Ghazizadeh3
1Department of Oral and Maxillofacial Surgery, Dental Implants Research Center, School of Dentistry, Isfahan University of Medical Sciences, Kermanshah, Iran.
Abstract:
Tricho-dento-osseous (TDO) syndrome is a multisystem congenital disorder that is known by bone, skin, and hair abnormalities. Primitive studies show different varieties of manifestations related to this disorder, which involve sclerotic bones, nail involvement, enamel hypoplasia, mandibular prognathism, and taurodontism. Although exploring different TDO cases revealed genetic mutations in all of them, they have many variations in phenotypic view. In this study, we report a case whose primary diagnosis was alopecia and came for extraction of her third molars, but after clinical and radiographic examination, it was found that the cause of her disease was something different.
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