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Skin Cancer

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

Clinical Applications of Epidermal Stem Cells

Clinical Applications of Epidermal Stem Cells

Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own...

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A Postoperative Evaluation Guideline for Computer-Assisted Reconstruction of the Mandible

A Postoperative Evaluation Guideline for Computer-Assisted Reconstruction of the Mandible

Published on: January 28, 2020

Evidence-Based Clinical Practice Guideline: Reconstruction after Skin Cancer Resection.

Andrew Chen¹, John G Albertini¹, Jeremy S Bordeaux¹

¹From the University of Connecticut; The Skin Surgery Center; University Hospitals Cleveland Medical Center/Case Western Reserve University; Kaiser Permanente; Duke University Medical Center; American Society of Plastic Surgeons; Galaria Plastic Surgery and Dermatology; Veterans Affairs Medical Center; Florida Center for Dermatology; Department of Dermatology, University of Pennsylvania Perelman School of Medicine; private practice; Cooper Medical Center, Rowan University; University of South Florida; University of Central Florida; University of California, Irvine; Piedmont Plastic Surgery and Dermatology; Pennsylvania State University; Rush University Medical Center; University of Illinois at Chicago; R. L. Roudebush Veterans Affairs Medical Center; University of California, Davis, Medical Center; University of Iowa Hospitals & Clinics; private practice; and Northwestern University.

Plastic and Reconstructive Surgery

|April 23, 2021

Summary

This summary is machine-generated.

Developing guidelines for skin cancer reconstruction, this study offers evidence-based recommendations on timing, anticoagulation, antibiotics, pain control, and follow-up. Further research is needed for robust clinical practice guidance.

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Area of Science:

Dermatology
Plastic Surgery
Evidence-Based Medicine

Background:

Skin cancer resection often necessitates complex reconstruction.
Diverse reconstructive techniques and clinical scenarios pose challenges for standardized management.

Purpose of the Study:

To develop evidence-based guidelines for post-skin cancer resection reconstruction.
To identify common elements and provide recommendations for improved patient care.

Main Methods:

Convened a multi-disciplinary work group with diverse stakeholders.
Conducted a systematic literature review.
Utilized the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) methodology for quality appraisal.

Main Results:

Generated recommendations on reconstruction timing, anticoagulation management, antibiotic use, pain control, and follow-up.
Distinguished between office-based and facility-based treatment options where applicable.
Identified areas with insufficient evidence for high-level recommendations.

Conclusions:

The guidelines address key aspects of skin cancer reconstruction.
Highlights the need for methodologically robust studies to further guide clinical practice.
Emphasizes the importance of a multi-disciplinary approach in managing reconstructive challenges.