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[Pseudobulbar affect in stroke patients in Argentina].

Matías Alet1, Constanza Segamarchi, Santiago Claverie

  • 1Sección de Enfermedades Cerebrovasculares, Servicio de Neurología. Hospital J.M. Ramos Mejía, Ciudad de Buenos Aires, Argentina.

Vertex (Buenos Aires, Argentina)
|April 23, 2021
PubMed
Summary

Pseudobulbar affect (PBA) is underdiagnosed after stroke. This study found PBA in 8 patients, highlighting the need for screening and differential diagnosis from depression.

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Epidemiology and risk factors of stroke in the Americas: a comprehensive narrative literature review.

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Area of Science:

  • Neurology
  • Psychiatry
  • Clinical Research

Background:

  • Pseudobulbar affect (PBA) involves exaggerated emotional responses like laughter or crying after neurological events.
  • PBA affects 11%-34% of post-stroke patients but is often underdiagnosed.
  • This study aimed to determine the frequency of PBA in a stroke patient cohort.

Purpose of the Study:

  • To investigate the prevalence of pseudobulbar affect (PBA) in patients following a stroke.
  • To assess the utility of specific scales in diagnosing PBA in this population.

Main Methods:

  • A prospective observational study conducted from June 2017 to June 2018.
  • Evaluated 50 patients with acute and chronic stroke, excluding those with severe psychiatric illness or cognitive impairment.
Keywords:
StrokeEmotion incontinencePseudobulbar affect

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  • Utilized the Pathological Laughing and Crying Scale (PLACS) and the Center for Neurological Studies-Lability Scale (CNS-LS) for diagnosis.

    • Main Results:

    • Of 50 patients, 8 (16%) met the diagnostic criteria for PBA (2 in chronic stroke, 6 in acute stroke).
    • Positive PLACS results were 21% (Group A) and 29% (Group B); positive CNS-LS results were 58% (Group A) and 26% (Group B).
    • Three patients diagnosed with PBA also had co-occurring depression.

    Conclusions:

    • Pseudobulbar affect requires screening in stroke survivors.
    • Differentiating PBA from post-stroke depression is crucial.
    • Relying on a single diagnostic scale may be insufficient for accurate PBA assessment.