Macroporous Polyzwitterionic Gels As Versatile Intermediates for the Fixation and Release of Anions

A new stable and functional polyzwitterion poly[1-(carboxymethyl)-4-methacrylamidopyridin-1-ium] was synthesized. The zwitterionic polymer shows its isoelectric point at a pH of 4.2, bidirectional pH responsiveness, and formation of dendritic fractal self-aggregated structures. Using this as a common intermediate, a simple, direct, and scalable single-step protocol was established to introduce various elementary anions like NO₃^-, HSO₄^-, H₂PO₄^-, F^-, Cl^-, Br^-, I^-, CH₃COO^-, and HCOO^- in their salt forms by reaction with the corresponding acids. FESEM studies on cross-linked polymeric hydrogels established the macroporous nature of these materials with their pore size in the range of 10-15 μm. Bidirectional swelling behavior was observed in these hydrogels from gel swelling kinetics and pH studies. Anion release studies in deionized water and buffer solutions showed ∼82 and ∼95% cumulative release for nitrate and phosphate anions, respectively, in 72 h. Our studies suggest that multifunctional polyzwitterionic gels are promising intermediates in the fixation and release of anions like nitrate and phosphate with potential applications in agriculture and healthcare.