Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Multivariate study of sleep EEG in depression.

M Kerkhofs1, C Kempenaers, P Linkowski

  • 1Department of Psychiatry, Erasme Hospital, University of Brussels, Belgium.

Acta Psychiatrica Scandinavica
|April 1, 1988
PubMed
Summary

Major depressive disorder subtypes and patient factors like age and gender significantly impact sleep EEG measures. Sleep patterns in depression are complex, influenced by multiple variables.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Clinical factors predicting treatment resistant depression: affirmative results from the European multicenter study.

Acta psychiatrica Scandinavica·2018
Same author

International Union of Basic and Clinical Pharmacology CIV: The Neurobiology of Treatment-resistant Depression: From Antidepressant Classifications to Novel Pharmacological Targets.

Pharmacological reviews·2018
Same author

Clinical correlates of augmentation/combination treatment strategies in major depressive disorder.

Acta psychiatrica Scandinavica·2018
Same author

Genetics of bipolar disorders.

Acta neuropsychiatrica·2016
Same author

Molecular genetic findings in mood disorders.

Acta neuropsychiatrica·2016
Same author

New molecular genetic findings in the genetics of affective disorders.

Acta neuropsychiatrica·2016

Area of Science:

  • Neuroscience
  • Psychiatry
  • Sleep Medicine

Background:

  • Major Depressive Disorder (MDD) is a heterogeneous condition.
  • Sleep disturbances are common in MDD patients.
  • Understanding factors influencing sleep EEG in depression is crucial.

Purpose of the Study:

  • To analyze the effects of four MDD subtypes on four sleep EEG variables.
  • To investigate the influence of age, gender, DST response, and depression severity on sleep EEG.
  • To identify specific factors affecting sleep EEG measures in depressed inpatients.

Main Methods:

  • Analysis of sleep electroencephalogram (EEG) variables.
  • Inclusion of 153 depressed inpatients.
  • Statistical analysis accounting for age, gender, dexamethasone suppression test (DST) response, and depression severity.

Related Experiment Videos

Main Results:

  • Age significantly impacted slow wave sleep.
  • Sleep efficiency and total sleep time varied with age and depression severity.
  • REM latency was influenced by endogenous subtype and gender, not other factors.

Conclusions:

  • Sleep EEG measures in depressed patients are multifactorial.
  • MDD subtypes, age, gender, and depression severity play distinct roles in sleep alterations.
  • Further research is needed to elucidate the complex interplay of these factors.