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Pulmonary embolism in the elderly.

W Busby1, A Bayer, J Pathy

  • 1University Department of Geriatric Medicine, Cardiff Royal Infirmary, South Glamorgan.

Age and Ageing
|May 1, 1988
PubMed
Summary
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Pulmonary emboli diagnosis in elderly patients lacked specific clinical signs, but anticoagulants were well-tolerated. Postmortem data suggest a decline in pulmonary embolism frequency among older individuals.

Area of Science:

  • Geriatric Medicine
  • Cardiology
  • Pulmonology

Background:

  • Pulmonary embolism (PE) is a significant cause of morbidity and mortality, particularly in elderly populations.
  • Early diagnosis and treatment are crucial for improving patient outcomes.

Purpose of the Study:

  • To investigate the diagnostic challenges and clinical features associated with pulmonary embolism in patients over 65 years of age.
  • To evaluate the tolerability of anticoagulant therapy in this demographic.
  • To analyze postmortem findings regarding the prevalence of PE in the elderly.

Main Methods:

  • Retrospective analysis of consecutive patients aged 65+ diagnosed with PE via ventilation-perfusion lung scan or necropsy.
  • Review of clinical features, diagnostic methods, and treatment outcomes.

Related Experiment Videos

  • Examination of postmortem data for trends in PE frequency.
  • Main Results:

    • No specific clinical features were found to be highly predictive of PE in this elderly cohort.
    • Deep-vein thrombosis (DVT) signs were present in 35% of patients.
    • Anticoagulant therapy was well-tolerated by all prescribed patients.
    • Postmortem findings indicated a decreasing frequency of PE in the elderly.

    Conclusions:

    • Clinical presentation of PE in the elderly is often non-specific, necessitating reliance on diagnostic imaging and necropsy.
    • Anticoagulation is a safe and effective treatment option for PE in older adults.
    • The observed decrease in PE frequency may suggest a reduction in associated risk factors in the aging population.