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Automated multi-class brain tumor types detection by extracting RICA based features and employing machine learning

Sadia Anjum1, Lal Hussain2,3,4, Mushtaq Ali1

  • 1Department of IT, Hazara University, Mansehra 21120, KPK, Pakistan.

Mathematical Biosciences and Engineering : MBE
|April 24, 2021
PubMed
Summary
This summary is machine-generated.

A new method using reconstruction independent component analysis (RICA) effectively detects multiple brain tumor types. This approach significantly improves diagnostic accuracy for pituitary, meningioma, and glioma, aiding early cancer detection.

Keywords:
feature extractiongliomaimage analysismachine learningmeningiomapituitary

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Area of Science:

  • Medical Imaging
  • Machine Learning in Oncology
  • Computational Neuroscience

Background:

  • Brain tumors are a leading global cause of cancer mortality.
  • Early detection of brain tumors significantly increases patient survival rates.
  • Accurate classification of tumor types (pituitary, meningioma, glioma) is crucial for effective treatment.

Purpose of the Study:

  • To introduce a novel feature extraction method, reconstruction independent component analysis (RICA), for multi-class brain tumor detection.
  • To evaluate the efficacy of machine learning classifiers, specifically Support Vector Machine (SVM) and Linear Discriminant Analysis (LDA), in classifying brain tumor types using RICA features.
  • To assess the diagnostic performance of the proposed RICA-based methodology for differentiating between pituitary, meningioma, and glioma.

Main Methods:

  • Proposed a novel reconstruction independent component analysis (RICA) for feature extraction from brain tumor images.
  • Employed Support Vector Machine (SVM) with quadratic and linear kernels, and Linear Discriminant Analysis (LDA) for classification.
  • Utilized 10-fold cross-validation for robust training and testing data validation.

Main Results:

  • Achieved high accuracy in multi-class brain tumor classification: pituitary (99.34%), meningioma (96.96%), and glioma (95.88%).
  • Demonstrated excellent performance metrics, including sensitivity (97.78%), specificity (100%), and AUC (up to 0.9892 for pituitary).
  • The RICA feature extraction method proved effective in distinguishing between different brain tumor types.

Conclusions:

  • The proposed RICA feature-based methodology shows significant potential for improving the diagnostic efficiency of multi-class brain tumor detection.
  • This approach can enhance prediction accuracy, contributing to better clinical outcomes.
  • The study highlights the value of advanced feature extraction techniques combined with machine learning for brain tumor classification.