Reprint of: Physiology of the Human Dental Pulp
1United States Public Health Service Hospital, Regional Primate Research Center, and Department of Physiology and Biophysics, University of Washington, Seattle, Washington.
Abstract:
Because of the unique encasement of the human dental pulp in a low-compliance environment, intrapulpal tissue pressure is of paramount importance in pulpal physiology. Tissue pressure is a local phenomenon, and the pathophysiology of pulp is characterized not by a sudden strangulation at the apex but by a circumferential spread of inflammation and necrosis from a site of initial injury. It is only when gross destruction of tissue has led to a loss of structural integrity that the pulp may become an isobaric chamber in which all areas are in hydrostatic communication.
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