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Cardiac catheterization is an invasive diagnostic technique used to identify and evaluate structural and functional diseases of the heart and major blood vessels. This technique diagnoses congenital heart disease, coronary artery disease, valvular heart disease, and coronary spasms and assesses ventricular function. It helps guide treatment decisions, including the need for revascularization procedures like percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) and...
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Porcine Liver Transplantation Without Veno-Venous Bypass As an Extended Criteria Donor Model
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Cardiac Intervention Before Liver Transplantation.

Ashraf Imam1, Cihan Karatas1, Nesimi Mecit1

  • 1Liver Transplantation Department, Koc University Hospital, Istanbul, Turkey.

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Coronary artery bypass grafting (CABG) is a safe option for patients with coronary artery disease awaiting liver transplantation (LT). This study found no mortality in patients who underwent CABG before LT.

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Area of Science:

  • Cardiology
  • Hepatology
  • Transplantation Surgery

Background:

  • Cardiovascular complications are a leading cause of mortality post-liver transplantation (LT).
  • Pre-transplant cardiac evaluation is crucial for patients undergoing LT.
  • Percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) are treatments for coronary artery disease.

Purpose of the Study:

  • To evaluate the safety and efficacy of cardiac interventions prior to LT.
  • To assess CABG as a treatment option for patients with coronary artery disease and end-stage liver disease.

Main Methods:

  • Retrospective, single-center study.
  • Included patients who underwent cardiac intervention (PCI or CABG) before LT for end-stage liver disease.
  • Data collected on patient demographics, procedures, and outcomes.

Main Results:

  • 29 of 51 patients had cardiac intervention before LT.
  • 24 patients had diagnostic PCI, 3 had therapeutic PCI with stent, and 2 had PCI failure requiring CABG.
  • The 2 CABG patients underwent live-related LT with no reported mortality.

Conclusions:

  • CABG is a valuable and safe treatment for cirrhotic patients with coronary artery disease awaiting LT, especially after PCI failure.
  • Live donor LT can serve as a backup for patients experiencing hepatic decompensation.