Related Experiment Video
Updated: Nov 8, 2025

12:21
The Mouse Round-window Approach for Ototoxic Agent Delivery: A Rapid and Reliable Technique for Inducing Cochlear Cell Degeneration
Published on: November 26, 2015
17.9K
The Third Mobile Window Effects in Otology/Neurotology
Ichiro Ota1, Masaharu Sakagami1, Tadashi Kitahara1
1Department of Otolaryngology-Head and Neck Surgery, Nara Medical University, Kashihara City, Nara, Japan.
The Journal of International Advanced Otology
|April 24, 2021
Summary
Inner ear fistulae create a "third mobile window," affecting sound conduction and causing large air-bone gaps. This phenomenon can mislead surgeons regarding persistent hearing loss after tympanoplasty.
Area of Science:
- Otolaryngology
- Neuro-otology
- Audiology
Background:
- Inner ear fistulae introduce an abnormal third mobile window, alongside the oval and round windows.
- This third mobile window disrupts normal sound wave transmission through the inner ear's perilymphatic spaces.
Purpose of the Study:
- To review the effects of the third mobile window phenomenon in otological diseases and surgeries.
- To clarify how inner ear fistulae cause significant air-bone gaps, particularly at low frequencies.
- To prevent misinterpretation of persistent air-bone gaps after ossicular reconstruction in tympanoplasty.
Main Methods:
- Review of existing literature and case examples concerning inner ear fistulae.
- Analysis of audiological findings, specifically pure-tone audiometry and air-bone gaps.
- Discussion of the impact of the third mobile window on sound conduction pathways.
Main Results:
- Inner ear fistulae create large air-bone gaps at low frequencies by altering sound wave mechanics.
- Air-conducted waves escape through the fistula, while bone-conducted waves are differentially affected.
- This leads to reduced bone conduction thresholds and a widened air-bone gap.
Conclusions:
- The third mobile window effect is a critical consideration in diagnosing and managing hearing loss associated with inner ear fistulae.
- Understanding this phenomenon is essential for accurate interpretation of audiometric results and surgical outcomes in otology.
- Surgeons must differentiate third mobile window effects from other causes of persistent air-bone gaps post-tympanoplasty.

