Related Experiment Video

Updated: Nov 8, 2025

Author Spotlight: Developing a Point-of-Care Hemoglobin Estimation Method for Anemia Management
05:35

Author Spotlight: Developing a Point-of-Care Hemoglobin Estimation Method for Anemia Management

Published on: January 19, 2024

1.1K

On-admission anemia predicts mortality in COVID-19 patients: A single center, retrospective cohort study

Seung Mi Oh1, John P Skendelas2, Eric Macdonald1

  • 1Department of Anesthesiology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

The American Journal of Emergency Medicine
|April 25, 2021
PubMed

Insights

Anemia on admission increases mortality risk in hospitalized COVID-19 patients. Moderate-severe anemia is linked to severe outcomes and death, suggesting anemia management is crucial for patient care.

Area of Science:

  • Internal Medicine
  • Infectious Diseases
  • Hematology

Background:

  • Anemia, a common condition, may impact COVID-19 severity.
  • Hemoglobin levels on admission could serve as a prognostic indicator for coronavirus disease 2019 (COVID-19).

Purpose of the Study:

  • To investigate the prognostic value of admission anemia in predicting severe outcomes and mortality in hospitalized COVID-19 patients.

Main Methods:

  • Retrospective cohort study of 733 adult patients with laboratory-confirmed SARS-CoV-2 infection.
  • Data collected from Montefiore Medical Center between March-June 2020.
  • Primary outcome: composite endpoint of in-hospital severe COVID-19 outcomes; Secondary outcome: in-hospital all-cause mortality.

Main Results:

  • Anemia was present in 59.8% of patients on admission.
  • Anemia on admission independently predicted all-cause mortality (OR 1.52).
  • Moderate-severe anemia (Hb < 11 g/dL) independently predicted both severe outcomes (OR 1.53) and mortality (OR 1.67).

Conclusions:

  • Admission anemia is an independent risk factor for mortality in COVID-19 patients.
  • Moderate-severe anemia is a significant predictor of severe COVID-19 outcomes.
  • Incorporating anemia assessment into COVID-19 patient management may improve risk stratification and care.
Abstract

Keywords:
AnemiaCOVID-19Emergency departmentHypoxic respiratory failureMortalitySepsis

More Related Videos

Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure05:16

Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure

Published on: June 10, 2025

352
Prediction of Red Blood Cell Antibody Significance Using the Monocyte-Macrophage Assay11:27

Prediction of Red Blood Cell Antibody Significance Using the Monocyte-Macrophage Assay

Published on: February 7, 2025

726

Related Concept Videos

Bioavailability Study Design: Healthy Subjects Versus Patients01:15

Bioavailability Study Design: Healthy Subjects Versus Patients

Bioavailability studies are essential for evaluating a drug's therapeutic efficacy and understanding its absorption patterns under various physiological conditions. Conducting such studies on target patient populations provides more relevant data by simulating real-world disease states. However, practical challenges often necessitate the use of young, healthy adult volunteers as study subjects.Patients may exhibit altered drug absorption patterns due to the effects of the disease itself,...
51
Pneumonia III: Complications and Assessment01:30

Pneumonia III: Complications and Assessment

Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
557
Bias in Epidemiological Studies01:29

Bias in Epidemiological Studies

Biases can arise at various stages of research, from study design and data collection to analysis and interpretation. Recognizing and addressing these biases is essential to ensure the validity and reliability of epidemiological findings.Broadly speaking, biases in epidemiology fall into three main categories: selection bias, information bias, and confounding. A more detailed description of possible biases is:  
919
Acute Kidney Injury IV: Diagnostic Studies and Prevention01:30

Acute Kidney Injury IV: Diagnostic Studies and Prevention

Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
119
Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
13.0K
Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
68