Related Experiment Video
Updated: Nov 8, 2025

Author Spotlight: Methodologies and Advancements of Chronic Pain Management Research
Published on: January 5, 2024
Nonopioid Approaches to Pain Management in Chronic Kidney Disease
1Division of Nephrology, Brookdale Department of Geriatrics and Palliative Medicine, Icahn School of Medicine at Mount Sinai, New York, NY.
Abstract:
Patients with chronic kidney disease (CKD) and end-stage renal disease experience high pain and symptom burden, but management of chronic pain in this population remains challenging. Recent studies have shown a high rate of opioid prescription and use in patients with kidney disease. However, the concern for opioid-related morbidity and mortality suggests a need to reconsider the safety and efficacy of opioid use in patients with CKD. In this review, we describe the current approaches to pain management in CKD, highlight the evolving opioid-related risks and kidney-specific concerns, and offer both pharmacologic and nonpharmacologic nonopioid strategies for pain management in patients with kidney disease, emphasizing the importance of using a multimodal approach to optimize pain control.
Related Concept Videos
Chronic Kidney Disease III: Interprofessional Care
Analgesia and Pain Management
Chronic Kidney Disease IV: Nursing Management
Opioid Analgesics: Synthetic and Semisynthetic Opioids
Chronic Kidney Disease I: Introduction
Acute Kidney Injury V: Interprofessional Care

