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Updated: Nov 8, 2025

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Emergency Care of Patients with Acute Ischemic Stroke
Adeel S Zubair1, Kevin N Sheth2
1Department of Neurology, Yale School of Medicine, New Haven, CT, USA.
Insights
Rapid management of acute ischemic stroke within the first hour, known as the golden hour, is critical for improving patient outcomes and reducing long-term disability. This review covers essential prehospital and in-hospital interventions, including advanced imaging and reperfusion therapies.
Area of Science:
- Neurology
- Emergency Medicine
- Public Health
Background:
- Stroke is a primary cause of death, disability, and long-term morbidity.
- Effective management of acute ischemic stroke significantly impacts patient prognosis.
- The initial hours post-stroke, termed the 'golden hour,' are crucial for intervention.
Purpose of the Study:
- To provide a comprehensive overview of acute ischemic stroke management.
- To emphasize the importance of timely interventions during the golden hour.
- To discuss current and emerging treatment strategies.
Main Methods:
- Literature review focusing on acute ischemic stroke management.
- Analysis of prehospital care protocols and initial patient evaluation.
- Examination of diagnostic imaging techniques and therapeutic interventions.
Main Results:
- Timely assessment including history, neurological examination, and advanced imaging is vital.
- Thrombolysis and endovascular therapy are key reperfusion strategies.
- Prompt treatment initiation in the golden hour improves functional outcomes.
Conclusions:
- Optimal acute ischemic stroke management requires a coordinated approach from prehospital to hospital settings.
- Early administration of reperfusion therapies, particularly within the golden hour, is paramount.
- Continued research and implementation of evidence-based protocols are essential for reducing stroke-related morbidity and mortality.
Abstract:
Stroke is a leading cause of morbidity and mortality and a major cause of long-term disability. Management of acute ischemic stroke in the first hours is critical to patient outcomes. This review provides an overview of acute ischemic stroke management, with a focus on the golden hour. Additional topics discussed include prehospital considerations and initial evaluation of the patient with history, examination, and imaging as well as treatment options, including thrombolysis and endovascular therapy.
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