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Updated: Aug 12, 2026

Depletion of Ribosomal RNA for Mosquito Gut Metagenomic RNA-seq
Published on: April 7, 2013
Unraveling mosquito metabolism with mass spectrometry-based metabolomics
Thomas D Horvath1, Shai Dagan2, Patricia Y Scaraffia3
1Department of Immunology and Pathology, Baylor College of Medicine, and Texas Children's Microbiome Center, Texas Children's Hospital, Houston, TX, 77030, USA.
Abstract:
Nearly half a million people die annually due to mosquito-borne diseases. Despite aggressive mosquito population-control efforts, current strategies are limited in their ability to control these vectors. A better understanding of mosquito metabolism through modern approaches can contribute to the discovery of novel metabolic targets and/or regulators and lead to the development of better mosquito-control strategies. Currently, cutting-edge technologies such as gas or liquid chromatography-mass spectrometry-based metabolomics are considered 'mature technologies' in many life-science disciplines but are still an emerging area of research in medical entomology. This review primarily discusses recent developments and progress in the application of mass spectrometry-based metabolomics to answer multiple biological questions related to mosquito metabolism.
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