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Functional Connectivity of the Cognitive Cerebellum
1Service de NeuroImagerie, Centre Hospitalier National d'Ophtalmologie des 15-20, Paris, France.
Frontiers in Systems Neuroscience
|April 26, 2021
Summary
The neocerebellum plays a crucial role in cognition and emotion, supporting complex tasks. Advanced functional connectivity mapping reveals its intricate organization within key brain networks.
Area of Science:
- Neuroscience
- Cognitive Neuroscience
- Neuroanatomy
Background:
- The neocerebellum's role in cognition and emotion is established through anatomical and clinical data.
- Telencephalization and neocerebellar expansion correlate with increased interconnections, supporting cognitive control.
- Human resting-state functional connectivity aids in neocerebellar functional parcellation.
Purpose of the Study:
- To elucidate the anatomo-functional organization of the human neocerebellum.
- To identify neocerebellar contributions to intrinsic brain networks involved in cognition and emotion.
Main Methods:
- Anatomical tracing
- Human clinical data analysis
- Stimulation functional imaging
- Resting-state functional connectivity analysis
Main Results:
- The neocerebellum is integral to major intrinsic brain networks (central executive, default mode, salience, attentional, language).
- The central executive network is prominently represented in the neocerebellar cortex.
- Neocerebellar zones for these networks are multiple, interdigitated, and spatially ordered.
Conclusions:
- The neocerebellum's complex organization enables monitoring and synchronization of cognitive and emotional networks.
- This likely involves the computation of internal models for cognitive and emotional regulation.
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