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A case of disseminated cryptococcus in an immunocompetent individual necessitating ventriculoperitoneal shunt

Daniel Myers1,2, Brooke McVaney2, Zachary Higginbotham2,3

  • 1Northwestern University, Chicago, IL, USA.

Medical Mycology Case Reports
|April 26, 2021
PubMed

Insights

Cryptococcosis, a rare fungal infection, can affect immunocompetent individuals. This case highlights disseminated cryptococcus presenting as meningitis and causing hydrocephalus in a young, healthy person.

Area of Science:

  • Infectious Diseases
  • Mycology
  • Neurology

Background:

  • Cryptococcosis is a fungal infection typically affecting immunocompromised individuals.
  • Caused by opportunistic yeasts like *Cryptococcus neoformans* and *Cryptococcus gattii*.
  • Rarely, it can manifest in immunocompetent hosts.

Observation:

  • A case of a young, immunocompetent individual presented with disseminated cryptococcosis.
  • The primary manifestation was cryptococcal meningitis.
  • This led to significant nonobstructive hydrocephalus.

Findings:

  • Disseminated cryptococcosis can occur in immunocompetent individuals.
  • Cryptococcal meningitis can result in severe neurological complications like hydrocephalus.
  • Ventriculoperitoneal (VP) shunt placement was necessary for management.

Implications:

  • Highlights the importance of considering cryptococcosis even in immunocompetent patients.
  • Underscores the potential for severe neurological sequelae.
  • Emphasizes the need for prompt diagnosis and management of cryptococcal meningitis and associated hydrocephalus.
Keywords:
CryptococcusHIVHepatitis CImmunocompetentVentriculoperitoneal shunt

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