Use of the XEN gel implant in a patient with aniridia-associated glaucoma

To report on the implantation of a XEN 45 gel implant in a patient with glaucoma associated with congenital aniridia.

A 60-year old man with familial congenital aniridia and glaucoma presented with intraocular pressure of 30 mmHg in his right eye despite maximal topical treatment with four medications. Implantation of a XEN gel stent was performed without complications after subconjunctival injection of mitomycin-C (0.1 mL of 0.02%). At the two-year follow-up, the patient's intraocular pressure was 12 mmHg with one topical medication. No needling of the filtering bleb was required. No excessive fibrosis of the conjunctiva or worsening of the existing keratopathy was noted.

The XEN 45 implant could be an option in the treatment of aniridia-associated glaucoma.