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Updated: Nov 8, 2025

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Published on: March 3, 2023
Endoscopic radiofrequency ablation for palliative treatment of hilar cholangiocarcinoma
Pedro Pereira1, Ana L Santos1, Rui Morais1
1Gastroenterology Department, Centro Hospitalar São João, Porto, Portugal.
Background And Aims:
Recent data support a role for endoscopic radiofrequency ablation (RFA) in unresectable cholangiocarcinoma by improving stent patency and overall survival.
Methods:
We describe 3 patients with inoperable cholangiocarcinoma with jaundice and cholestasis who were recommended palliative chemotherapy. They underwent endoscopic retrograde cholangiopancreatography with single-operator cholangioscope and intraductal RFA.
Results:
The procedures were performed without adverse events in all patients, with clinical and analytical improvement 1 month later.
Conclusions:
RFA is a promising and safe palliative treatment in patients with unresectable cholangiocarcinoma.

