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Campylobacter pylori gastritis
M J Mahony1, J I Wyatt, J M Littlewood
1Department of Paediatrics, St James's University Hospital, Leeds.
Insights
Campylobacter pylori (C pylori) infection was found in 24% of children undergoing upper gastrointestinal endoscopy. This bacterium was present in 88% of pediatric gastritis cases examined.
Area of Science:
- Pediatric Gastroenterology
- Microbiology
- Histopathology
Background:
- Campylobacter pylori (C pylori) is linked to type B non-autoimmune gastritis in adults.
- The prevalence and association of C pylori with gastritis in pediatric populations require further investigation.
Purpose of the Study:
- To determine the prevalence of C pylori in children undergoing upper gastrointestinal endoscopy.
- To assess the association between C pylori and gastritis in pediatric gastric biopsy specimens.
Main Methods:
- Retrospective analysis of 38 gastric biopsy specimens from children.
- Histological examination of biopsy specimens for gastritis.
- Detection of C pylori via appropriate diagnostic methods (details not specified in abstract).
Main Results:
- C pylori was identified in 9 out of 38 (24%) pediatric specimens.
- Gastritis was histologically confirmed in 10 specimens.
- C pylori was present in 8 out of the 10 (80%) cases with gastritis.
Conclusions:
- C pylori colonisation is prevalent in children undergoing upper gastrointestinal endoscopy.
- A strong association exists between C pylori and gastritis in the studied pediatric cohort.
Abstract:
Campylobacter pylori colonisation of the stomach is strongly associated with type B non-autoimmune gastritis in adults. In a retrospective study of 38 gastric biopsy specimens taken during upper gastrointestinal endoscopy in children attending this hospital we found C pylori in nine (24%). Ten biopsy specimens showed histological evidence of gastritis and C pylori was found in eight.