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Updated: Nov 8, 2025

Isolation and Adoptive Transfer of High Salt Treated Antigen-presenting Dendritic Cells
Published on: March 5, 2019
[ROLE OF THE IMMUNE SYSTEM IN THE PATHOGENESIS OF HYPERTENSION]
Shiri Weinstein1, Avshalom Leibowitz1,2
1Internal Medicine D, The Chaim Sheba Medical Center, Tel- Hashomer Affiliated to the Sackler Faculty of Medicine, Tel Aviv University, Tel-Aviv.
Introduction:
The understanding that the immune system has a role in the pathogenesis of essential hypertension was established over the last few decades, with many different works showing that manipulating the immune system effects blood pressure. Pro-inflammatory cell activation can cause hypertension while anti-inflammatory cell activation restrains it. These activations involve different cell types, cytokine and chemokine secretions, and affect different target organs. Additionally, there is evidence that hypertension itself may affect the immune system. This article reviews the main findings in this area.
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