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Updated: Nov 8, 2025

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Ambulatory Care Fragmentation and Incident Stroke
Lisa M Kern1, Joanna B Ringel1, Mangala Rajan1
1Weill Cornell Medicine New York NY.
Fragmented ambulatory care, or care spread across many providers, is linked to increased stroke risk, particularly for Black individuals with poor health. This finding highlights disparities in stroke incidence and care coordination.
Area of Science:
- Geriatric Medicine
- Cardiovascular Epidemiology
- Health Services Research
Background:
- Fragmented ambulatory care is associated with increased healthcare utilization, including emergency department visits and hospitalizations.
- Understanding the impact of care fragmentation on specific health outcomes like stroke is crucial for targeted interventions.
Purpose of the Study:
- To investigate the association between fragmented ambulatory care and the risk of incident stroke.
- To stratify this association by participants' health status and race.
Main Methods:
- Secondary analysis of the REGARDS study (2003-2016) including 12,510 participants aged ≥65 years with linked Medicare claims and no prior stroke.
- Care fragmentation measured using the reversed Bice-Boxerman index.
- Poisson models used to assess the association between fragmentation and incident stroke.
Main Results:
- No overall association between high versus low care fragmentation and incident stroke.
- A trend towards higher stroke rates in participants with fair/poor health and high fragmentation (14.8 vs. 10.4 per 1000 person-years).
- A significant association between high fragmentation and higher stroke rates among Black participants with fair/poor health (19.3 vs. 10.3 per 1000 person-years; P=0.02).
Conclusions:
- Highly fragmented ambulatory care is an independent risk factor for incident stroke in Black individuals with fair or poor self-rated health.
- This highlights a critical disparity in stroke risk related to care coordination challenges within specific demographic groups.
- Further research into interventions addressing care fragmentation for vulnerable populations is warranted.
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