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Updated: Jun 23, 2026

The WATCHMAN Left Atrial Appendage Closure Device for Atrial Fibrillation
Published on: February 28, 2012
Right Atrial Appendage Thrombus in Atrial Fibrillation: A Case Report and Review of the Literature
Aaron C Richardson1, Michael Omar1, Gladys Velarde1
1University of Florida, Jacksonville, FL, USA.
Insights
Atrial fibrillation (Afib) patients can develop clots in the right atrial appendage (RAA), though less common than in the left. Management for RAA clots should mirror LAA clot treatment, involving anticoagulation and delayed cardioversion.
Area of Science:
- Cardiology
- Electrophysiology
- Thrombosis
Background:
- Atrial fibrillation (Afib) is a prevalent heart rhythm disorder affecting 2-3% of adults in Europe and North America.
- Left atrial appendage (LAA) thrombi are common in Afib, leading to stroke and systemic events.
- Right atrial appendage (RAA) thrombi in Afib patients are less understood but pose risks like pulmonary embolism.
Observation:
- Right atrial appendage thrombi formation in Afib patients is not well understood.
- RAA thrombi can lead to pulmonary embolism or paradoxical embolization.
- The prevalence and clinical impact of RAA thrombi require further investigation.
Findings:
- Management strategies for RAA thrombi should align with those for LAA thrombi.
- Treatment includes anticoagulation with warfarin to maintain an international normalized ratio of 2 to 3.
- Delaying cardioversion is a recommended management step for RAA thrombi.
Implications:
- Standardized management protocols for RAA thrombi can improve patient outcomes.
- Further research is needed to fully elucidate the prevalence and complications of RAA thrombi.
- This understanding can guide clinical decision-making in Afib patients with RAA thrombi.
Abstract:
Atrial fibrillation (Afib) is the most common abnormal heart rhythm in adults and has become a significant public health concern affecting 2% to 3% of the population in Europe and North America. Left atrial appendage (LAA) thrombi is the source of 90% of left-sided cardiac thrombi in patients with Afib, which can cause stroke and other systemic vascular events. Right atrial appendage (RAA) thrombi formation in Afib is much less common but complications include pulmonary embolism or paradoxical migration across patent foramen ovale with risk of systemic embolization. The prevalence and subsequent clinical complications of RAA thrombi formation in Afib patients is not well understood. Management of RAA thrombi should be similar to that of LAA thrombi which includes delaying cardioversion and anticoagulating with warfarin therapy to achieve international normalized ratio of 2 to 3.
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