Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Birth Control Methods01:22

Birth Control Methods

5.4K
Vasectomy is a surgical form of male sterilization that involves severing and sealing the vasa deferentia, preventing sperm from mixing with semen during ejaculation. Because a vasectomy does not impact the testes' ability to produce testosterone, hormone levels, libido, and sexual function generally remain unchanged. While vasectomy is highly effective in preventing pregnancy, with a success rate near 99.85%, rare cases of recanalization (spontaneous reconnection) can occur. Although...
5.4K
Primary Healthcare Services01:30

Primary Healthcare Services

1.7K
Primary care promotes wellness and prevents disease. This care includes health promotion, education, protection (such as immunizations), early disease screening, and environmental considerations. Settings providing this type of healthcare include physician offices, public health clinics, school nursing, and community health nursing.
In 1978, international leaders convened in Alma-Ata, Kazakhstan, for what would be a pivotal event in global health. The Alma-Ata Declaration was the first to call...
1.7K
Preventive Healthcare Services01:30

Preventive Healthcare Services

1.2K
Preventive healthcare services keep people healthy via frequent check-ups, screening, and counseling. They primarily aid in disease prevention rather than treating an acute or chronic illness. Preventive treatment also keeps individuals productive and energetic, allowing them to work well into their retirement years. Examples of preventive care services include:
1.2K
Secondary Healthcare System01:11

Secondary Healthcare System

1.8K
Secondary healthcare is offered by a specialist, generally in hospitals or clinics for patients referred by primary healthcare providers. It occurs when a person has an illness or injury that requires specific medical care. Secondary care is often referred to as acute care. Secondary care can range from uncomplicated care to repair a minor laceration or treat a strep throat infection to more complicated emergent care, such as treating a head injury sustained in an automobile accident. Whatever...
1.8K
Gonadal and Placental Hormones01:24

Gonadal and Placental Hormones

2.3K
The gonads, namely the testes in males and the ovaries in females, are pivotal in producing gonadal hormones that orchestrate the intricate processes of sexual development and reproduction.
In males, testosterone is the primary gonadal androgen. It plays a central role in the maturation of male reproductive organs — the penis and testes. Additionally, testosterone is instrumental in the development of secondary sexual characteristics — a deep voice as well as facial and pubic hair...
2.3K
Drugs for Peptic Ulcer Disease: Prostaglandin Analogs as Mucosal Protective Agents01:20

Drugs for Peptic Ulcer Disease: Prostaglandin Analogs as Mucosal Protective Agents

757
The gastric mucosa produces prostaglandins E2 (PGE2) and prostacyclin (PGI2), crucial in maintaining gastric health. They exert cytoprotective effects, including increasing bicarbonate secretion, releasing protective mucin, reducing gastric acid output, and preventing harmful vasoconstriction. These effects are mediated through various receptors, such as EP1, EP2, EP3, and EP4.
Non-steroidal anti-inflammatory drugs (NSAIDs) can induce peptic ulcers by inhibiting cyclooxygenase, decreasing...
757

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

An X-linked sex determination mechanism in cannabis and hop.

Nature communications·2026
Same author

Risk Factors for a Primary Cesarean Delivery in Pregnancies Complicated by Pregestational Diabetes.

International journal of women's health·2026
Same author

A haplotype-resolved, chromosome-scale genome assembly for the southern live oak, Quercus virginiana.

G3 (Bethesda, Md.)·2026
Same author

Lifestyle Modifications Prior to Pregnancy and Their Impact on Maternal and Perinatal Outcomes: A Review.

Journal of clinical medicine·2025
Same author

An X-linked sex determination mechanism in cannabis and hop.

bioRxiv : the preprint server for biology·2025
Same author

Maternal and cord-blood inflammatory markers and BDNF in diabetic vs non-diabetic pregnancies.

medRxiv : the preprint server for health sciences·2025

Related Experiment Video

Updated: Nov 8, 2025

Reproductive Techniques for Ovarian Monitoring and Control in Amphibians
04:37

Reproductive Techniques for Ovarian Monitoring and Control in Amphibians

Published on: May 12, 2019

16.0K

17 Alpha-hydroxyprogesterone caproate use in a rural state.

Taylor Ghahremani1, Amy Phillips1, Everett F Magann1

  • 1Department of Obstetrics and Gynecology, University of Arkansas for Medical Sciences College of Medicine, Little Rock, AR, USA.

The Journal of Maternal-Fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
|April 26, 2021
PubMed
Summary

This study found that 17 alpha-hydroxyprogesterone caproate (17OHP) injections did not reduce recurrent preterm delivery risk in women with a history of preterm birth. Results were similar to a second study, despite a similar patient population to the initial trial.

Keywords:
17 OHPpregnancypreterm birthpreterm preventionrecurrent preterm delivery

More Related Videos

Renal Capsule Xenografting and Subcutaneous Pellet Implantation for the Evaluation of Prostate Carcinogenesis and Benign Prostatic Hyperplasia
08:38

Renal Capsule Xenografting and Subcutaneous Pellet Implantation for the Evaluation of Prostate Carcinogenesis and Benign Prostatic Hyperplasia

Published on: August 28, 2013

25.7K
Methods for Studying Uterine Contributions to Pregnancy Establishment in an Ovariectomized Mouse Model
06:49

Methods for Studying Uterine Contributions to Pregnancy Establishment in an Ovariectomized Mouse Model

Published on: April 7, 2023

1.9K

Related Experiment Videos

Last Updated: Nov 8, 2025

Reproductive Techniques for Ovarian Monitoring and Control in Amphibians
04:37

Reproductive Techniques for Ovarian Monitoring and Control in Amphibians

Published on: May 12, 2019

16.0K
Renal Capsule Xenografting and Subcutaneous Pellet Implantation for the Evaluation of Prostate Carcinogenesis and Benign Prostatic Hyperplasia
08:38

Renal Capsule Xenografting and Subcutaneous Pellet Implantation for the Evaluation of Prostate Carcinogenesis and Benign Prostatic Hyperplasia

Published on: August 28, 2013

25.7K
Methods for Studying Uterine Contributions to Pregnancy Establishment in an Ovariectomized Mouse Model
06:49

Methods for Studying Uterine Contributions to Pregnancy Establishment in an Ovariectomized Mouse Model

Published on: April 7, 2023

1.9K

Area of Science:

  • Obstetrics and Gynecology
  • Maternal-Fetal Medicine
  • Pharmacology

Background:

  • 17 alpha-hydroxyprogesterone caproate (17OHP) is a medication used to prevent recurrent preterm delivery in women with a history of preterm birth.
  • Conflicting study results exist regarding 17OHP's effectiveness, with one trial showing significant reduction and another showing no benefit.
  • Discrepancies in study populations have been cited as a potential reason for differing outcomes.

Approach:

  • This retrospective review examined 17OHP's effectiveness in a rural US state, focusing on a patient population similar to the original Meis trial.
  • The study analyzed data from January 2014 to December 2018, using logistic regression to assess the relationship between 17OHP injections and preterm delivery.
  • 268 women with a history of preterm delivery were categorized into three groups based on the number of 17OHP injections received (0, 1-10, >10).

Key Points:

  • Despite efforts to make 17OHP available due to cost and compounding issues, the study found no association between 17OHP injections and a reduction in preterm delivery.
  • The patient population in this rural US state was similar to that of the original Meis trial.
  • The findings align more closely with a subsequent study that reported no decrease in recurrent preterm delivery risk.

Conclusions:

  • This investigation suggests that 17OHP injections may not be effective in preventing recurrent preterm delivery in women with a prior history, even in a population similar to the initial positive trial.
  • The results highlight the need for further research to understand the variable effectiveness of 17OHP.
  • Healthcare providers should consider these findings when discussing treatment options for preterm birth prevention.