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Assisted Fluid Management Software Guidance for Intraoperative Fluid Administration.
Anesthesiology
|April 26, 2021
Summary
Software-guided fluid management during noncardiac surgery improved stroke volume increases compared to clinician-initiated boluses. This automated approach shows promise for optimizing intraoperative fluid administration and patient outcomes.
Area of Science:
- Anesthesiology
- Critical Care Medicine
- Surgical Fluid Management
Background:
- Intravenous fluid administration during noncardiac surgery is highly variable, leading to potential complications from excessive or inadequate fluid delivery.
- Current goal-directed management strategies are often complex and difficult to implement in practice.
- The Acumen Assisted Fluid Management software was developed to simplify and guide optimal fluid administration.
Purpose of the Study:
- To evaluate the performance of the Acumen Assisted Fluid Management software in guiding intravenous fluid administration during noncardiac surgery.
- To compare the effectiveness of software-recommended fluid boluses versus clinician-initiated boluses in achieving desired stroke volume increases.
- To assess the potential of automated fluid responsiveness assessment in optimizing intraoperative fluid management.
Main Methods:
- A multicenter, prospective, single-arm cohort study involving 330 adult patients undergoing moderate- to high-risk noncardiac surgery.
- Clinicians selected fluid strategies targeting specific stroke volume (SV) increases (10%, 15%, or 20%) post-fluid bolus.
- Fluid management software prompted "test" or "recommended" boluses, with clinicians able to accept, decline, or initiate "user" boluses.
Main Results:
- Software-recommended boluses achieved desired SV increases in 66% of cases, significantly higher than the 30% reference rate.
- Clinician-initiated boluses resulted in desired SV increases in only 41% of instances (P < 0.0001).
- The mean SV increase was significantly greater with software-recommended boluses (14.2 ± 13.9%) compared to clinician-initiated boluses (8.3 ± 12.1%).
Conclusions:
- Fluid boluses recommended by the Acumen software were more effective in achieving desired stroke volume increases than those initiated by clinicians.
- The software demonstrated a higher success rate and greater absolute increase in stroke volume.
- Automated assessment of fluid responsiveness via this software may enhance intraoperative fluid management during noncardiac surgery.
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