Factors Associated with Antidepressant Medication Non-adherence
Nirmal Raj Marasine1, Sabina Sankhi2
1Department of Pharmacy, Karnali College of Health Science, Gaushala, Kathmandu, Nepal
Turkish Journal of Pharmaceutical Sciences
|April 27, 2021
Summary
Antidepressant medication non-adherence in depression patients is linked to forgetfulness, side effects, and poor physician communication. Improving adherence requires better patient-provider relationships and simpler medication plans.
Area of Science:
- Psychiatry
- Pharmacology
- Public Health
Background:
- Medication non-adherence is a significant challenge in depression treatment.
- Non-adherence increases relapse risk and diminishes patient quality of life.
Purpose of the Study:
- To review and summarize factors contributing to antidepressant medication non-adherence in depression patients.
- To identify key patient, medication, healthcare system, and sociocultural factors influencing adherence.
Main Methods:
- Literature search conducted on PubMed/Medline and Google Scholar.
- Included English-language, peer-reviewed articles from January 2000 to December 2019.
- Focused on studies analyzing non-compliance factors in depressive disorders.
Main Results:
- Identified patient factors: forgetfulness, comorbidities, misconceptions.
- Highlighted medication factors: polypharmacy, side effects, pill burden, cost.
- Noted healthcare system factors: physician-patient interactions.
- Included sociocultural factors: beliefs, stigma, and logistic challenges.
Conclusions:
- Strengthening physician-patient relationships is crucial for improving adherence.
- Simplifying medication regimens can enhance patient compliance.
- Addressing patient misconceptions with scientific information is vital.
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