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Updated: Nov 8, 2025
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Magnetic Resonance Imaging Quantification of Pulmonary Perfusion using Calibrated Arterial Spin Labeling
Published on: May 30, 2011
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Measuring Perfusion: Intravoxel Incoherent Motion MR Imaging
1University and ETH Zürich, Institute for Biomedical Engineering, Gloriastrasse 35, Zürich 8092, Switzerland; Ai Medical AG, Goldhaldenstr 22a, Zollikon 8702, Switzerland.
Magnetic Resonance Imaging Clinics of North America
|April 27, 2021
Summary
Intravoxel incoherent motion (IVIM) perfusion MRI uses diffusion-weighted imaging to reveal blood flow information locally and quantitatively, without contrast agents. This review explores the IVIM method and its clinical uses.
Area of Science:
- Magnetic Resonance Imaging (MRI)
- Medical Physics
- Radiology
Background:
- Diffusion-weighted MRI (DWI) signal is affected by blood motion.
- Perfusion information can be extracted from DWI using specific parameters and postprocessing.
- Intravoxel incoherent motion (IVIM) is a technique that quantifies perfusion from DWI.
Purpose of the Study:
- To review the intravoxel incoherent motion (IVIM) perfusion MRI method.
- To discuss the clinical applications of IVIM perfusion MRI.
Main Methods:
- Utilizes diffusion-weighted MR imaging (DWI) sequences.
- Applies appropriate sequence parameters and postprocessing methods.
- Analyzes signal changes influenced by blood motion.
Main Results:
- IVIM provides local and quantitative perfusion information.
- Perfusion data is acquired without the need for intravenous contrast media.
- DWI signal inherently contains perfusion information.
Conclusions:
- IVIM is a valuable technique for assessing tissue perfusion.
- Its non-invasive nature and quantitative output offer significant clinical potential.
- Further exploration of IVIM's clinical applications is warranted.
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