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Overview of Diffusion Tensor, Diffusion Kurtosis, and Q-space Imaging and Software Tools.

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Summary

This review covers diffusion-weighted MR imaging (dMRI) and its processing software. It presents a standardized dMRI protocol for mapping tissue microstructure in clinical settings.

Keywords:
DKIDSIDTIDiffusion kurtosisDiffusion spectrum imagingDiffusion tensor imaging

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Area of Science:

  • Medical Imaging
  • Neuroscience
  • Biophysics

Background:

  • Diffusion-weighted MR imaging (dMRI) is crucial for assessing tissue microstructure.
  • Existing dMRI protocols and software tools vary, hindering standardization.
  • Accurate analysis of clinical dMRI data is essential for diagnosis and research.

Purpose of the Study:

  • To provide an up-to-date review of diffusion-weighted MR imaging (dMRI) techniques.
  • To survey widely used software tools for processing and analyzing clinical dMRI data.
  • To present a consolidated dMRI protocol for clinical applications.

Main Methods:

  • Literature review of current dMRI methods and software.
  • Description of a standardized dMRI protocol.
  • Discussion of tissue microstructural attribute mapping using dMRI.

Main Results:

  • An overview of contemporary dMRI techniques and available software.
  • A proposed consolidated dMRI protocol for clinical use.
  • Demonstration of dMRI's capability in mapping tissue microstructure.

Conclusions:

  • Standardized dMRI protocols are needed for reliable clinical application.
  • The presented protocol facilitates consistent mapping of microstructural attributes.
  • This work aids researchers and clinicians in utilizing dMRI effectively.