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Published on: December 2, 2012
Neurological Melioidosis Presenting as Rhombencephalitis, Optic Neuritis, and Scalp Abscess with Meningitis: A Case
Aparajita Chatterjee1, Kavitha Saravu2, Chiranjay Mukhopadhyay3
1Department of Neurology, Kasturba Medical College, Manipal Academy of Higher Education (MAHE), Manipal, Karnataka, India.
Abstract:
Melioidosis is an under recognized infectious disease which may rarely present with neurological involvement. Neurological melioidosis has protean manifestations, and in this case series we present 3 patients diagnosed from a single center in southern India. The clinical presentation of the patients we describe includes rhomb-encephalitis, scalp infection with subdural and meningeal involvement, and optic neuritis associated with pulmonary melioidosis. We discuss the possible mechanism of involvement of the nervous system, and the recommended treatment. Diagnosis of melioidosis requires a high index of suspicion and should be considered in endemic areas. Through this series we hope to improve the awareness of this infection and its neurological presentation.
Insights
Neurological melioidosis, a rare infectious disease complication, presents varied symptoms like rhomb-encephalitis and optic neuritis. Early diagnosis and treatment are crucial for better outcomes in endemic regions.
Area of Science:
- Infectious Diseases
- Neurology
- Microbiology
Background:
- Melioidosis is an under-recognized infectious disease caused by Burkholderia pseudomallei.
- Neurological involvement in melioidosis is rare but presents with diverse clinical manifestations.
- Prompt diagnosis and management are essential for improving patient outcomes.
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