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Related Concept Videos

Drug Delivery: Parenteral Route01:29

Drug Delivery: Parenteral Route

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The parenteral route is a critical method of drug administration. It delivers compounds directly into the systemic circulation and bypasses the gastrointestinal tract. This approach is particularly advantageous for drugs that exhibit poor absorption or instability when administered orally.
There are three primary parenteral routes: intravenous (IV), intramuscular (IM), and subcutaneous (SC). The IV route introduces the drug directly into the bloodstream, ensuring immediate action. The IM route...
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Drug Delivery: Miscellaneous Routes01:22

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Drug delivery methods like oral inhalation, nasal sprays, transdermal patches, eye drops, intravitreal injection,  and rectal administration provide localized effects with reduced toxicity.
Oral inhalation and nasal sprays swiftly transfer drugs across the respiratory epithelium's mucosal layer. Inhaled glucocorticoids and bronchodilators directly target lung conditions such as asthma, while fluticasone nasal spray mitigates allergic rhinitis.
Transdermal patches transport drugs...
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Drug Accumulation During Multiple Dosing: Repetitive IV Injections01:21

Drug Accumulation During Multiple Dosing: Repetitive IV Injections

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Calculating drug dosage and accumulation in multiple-dose regimens is crucial for achieving therapeutic efficacy while avoiding toxicity. This involves determining the plasma drug concentrations over time to optimize dosing schedules. The principle of superposition is fundamental in this process, allowing for the prediction of drug concentration in plasma following multiple doses based on single-dose data.The principle of superposition asserts that the plasma concentration-time curves from...
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Routes of Drug Administration: Parenteral01:25

Routes of Drug Administration: Parenteral

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The administration of drugs via parenteral routes allows for direct drug introduction into the systemic circulation, resulting in high bioavailability because the medication bypasses the harsh conditions of the gastrointestinal tract and hepatic metabolism.
The intravenous route (IV) of drug administration can be further categorized into two types. The bolus injection administers the entire dose rapidly, while an intravenous infusion slowly delivers smaller doses steadily.
The IV route is often...
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Local Anesthetics: Common Agents and Their Applications01:23

Local Anesthetics: Common Agents and Their Applications

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Local anesthetics (LAs) are commonly used for various applications in medical and dental procedures. Some of the common agents used are cocaine, lidocaine, and bupivacaine.
Cocaine is an ester of benzoic acid and methylecgogine. It is used to anesthetize and vasoconstrict locally. Currently, it is used primarily for topical applications. It is beneficial for surgeries on the upper respiratory tract, providing anesthesia and shrinking the mucosa. Cocaine in the form of cocaine hydrochloride is...
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Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia01:16

Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia

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Intravenous regional anesthesia or the Bier block technique is used to anesthetize a specific limb or extremity. It uses exsanguinated or blood-drained vessels to transport local anesthetics or LAs to the peripheral nerve trunks. Lidocaine without vasoconstrictors like epinephrine is most commonly used for this technique. Other drugs used are prilocaine, ropivacaine, and chloroprocaine. Bupivacaine is not recommended for this technique due to its high cardiac toxicity.
One of the advantages of...
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An Alternative and Validated Injection Method for Accessing the Subretinal Space via a Transcleral Posterior Approach
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Midlevel Injectable Practice Patterns in Dermatology and Plastic Surgery Offices.

Lauren Nesi1, Matthew Belcher, Ashley Decker

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Summary

While most physicians exclusively perform cosmetic injections, a notable percentage of dermatology and plastic surgery practices utilize nurse practitioners and physician assistants for these procedures, with varying supervision levels.

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Area of Science:

  • Medical Aesthetics
  • Dermatology Practice Management
  • Plastic Surgery Procedures

Background:

  • Limited understanding of physician delegation for cosmetic procedures to midlevel providers.
  • Need to clarify current practice patterns in aesthetic medicine.

Purpose of the Study:

  • To evaluate how dermatology and plastic surgery practices manage the administration of neurotoxin and dermal filler injections.
  • To identify the roles of physicians versus midlevel providers in performing cosmetic injectables.

Main Methods:

  • Surveyed 492 dermatology and plastic surgery practices across 10 major US metropolitan areas.
  • Gathered data on practice patterns regarding who performs injectable procedures.

Main Results:

  • Physicians exclusively perform injections in most dermatology and plastic surgery practices.
  • 18.35% of dermatology and 25.4% of plastic surgery practices involve nurse practitioners and physician assistants in performing injectables.
  • Physician supervision levels for midlevel providers administering injectables are variable.

Conclusions:

  • Majority of practices rely solely on physicians for neurotoxin and filler injections.
  • Variable physician oversight exists when midlevel providers perform injectables.
  • A small fraction of plastic surgery practices permit midlevel providers to perform injectables without physician involvement.