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Dissecting the Management and Outcomes of Thoracic Aortovascular Disease During the COVID-19 Pandemic
Iain McPherson1, Nicholas Chilvers2, Kathrin Freystaetter1
1Department of Cardiothoracic Surgery, Freeman Hospital, Newcastle-upon-Tyne, United Kingdom.
Insights
Thoracic aortovascular interventions remained safe during the COVID-19 pandemic, with comparable outcomes to pre-pandemic levels. This included patients with higher mortality risks and more urgent cases, demonstrating resilience in cardiovascular care.
Area of Science:
- Cardiovascular Surgery
- Vascular Intervention
- Epidemiology
Background:
- The COVID-19 pandemic significantly disrupted elective surgeries, including critical aortovascular interventions.
- Early intervention for aortovascular diseases is crucial and cannot be postponed.
- Evaluating the safety and outcomes of thoracic aortovascular procedures during the pandemic's peak is essential.
Purpose of the Study:
- To assess the provision and outcomes of thoracic aortovascular interventions during the COVID-19 pandemic.
- To compare patient characteristics and procedural outcomes between pandemic and pre-pandemic periods.
Main Methods:
- Prospective data collection from three tertiary cardiovascular centers.
- Comparison of open and endovascular thoracic aortovascular interventions between January-May 2020 (pandemic) and January-May 2019 (pre-pandemic).
- Analysis of baseline demographics, cardiovascular risk, COVID-19 screening, and primary outcomes including mortality, ICU/hospital stay, stroke, and spinal cord injury.
Main Results:
- Patients in 2020 presented with higher EuroSCORE II, more prior cardiac/aortic interventions, and a greater proportion of urgent cases.
- No significant differences were observed in 30-day mortality, ICU/hospital length of stay, post-operative stroke, or spinal cord injury between the two periods.
- Intra-operative mortality was low in both groups, with zero in 2020 and one in 2019.
Conclusions:
- Thoracic aortovascular interventions were safely performed during the COVID-19 pandemic.
- Outcomes remained comparable to pre-pandemic levels despite increased patient risk and case urgency.
- The study highlights the feasibility and safety of continuing essential cardiovascular interventions amidst a global health crisis.
Objective:
The COVID-19 pandemic has forced the cancellation of planned surgery and led to significant surgical service reductions. Early intervention in aortovascular disease is often critical and cannot be deferred despite these reductions. There is urgent need to evaluate the provision and outcomes of thoracic aortovascular intervention during the peak of the pandemic.
Methods:
Prospective data was collected for patients receiving open and endovascular thoracic aortovascular intervention over two-time points; January-May 2020 and January-May 2019 at three tertiary cardiovascular centres. Baseline demographics, cardiovascular risk and COVID-19 screening results were noted. Primary outcomes were median length of intensive care unit and hospital stay, intra-operative mortality, 30-day mortality, post-operative stroke, and spinal cord injury.
Results:
Patients operated in 2020 (41) had significantly higher median EuroSCORE II than 2019 (53) (7.44 vs. 5.86, P = 0.032) and rates of previous cardiac (19.5% vs. 3.8%, P = 0.019), aortic (14.6% vs. 1.9%, P = 0.041), and endovascular (22.0% vs. 3.8%, P = 0.009) intervention. There was an increase in proportion of urgent cases in 2020 (31.7% vs. 18.9%). There were no intra-operative deaths in 2020 and 1 in 2019 (P = 1.00). There were no significant differences (P ≥ 0.05) in 30-day mortality (4.9% vs. 13.2%), median intensive care unit length of stay (72 vs. 70 hr), median hospital length of stay (8 vs. 9 days), post-operative stroke (3 vs. 6), or spinal cord injury (2 vs. 1) between 2020 and 2019 respectively.
Conclusions:
Despite the increased mortality risk of patients and urgency of cases during COVID-19, complicated by the introduction of cohorting and screening regimens, thoracic aortovascular intervention remained safe with comparable in outcomes to pre-COVID-19.
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