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Updated: Nov 8, 2025

Laparoscopic Choledochal Cyst Excision and Roux-en-Y Choledochojejunostomy in Adults
Published on: February 28, 2025
CLOVES Syndrome Diagnosis and Treatment in an Adult Patient
Joana Ferreira1, Juan Carlos López Gutiérrez2, Alexandre Carneiro3
1Life and Health Science Research Institute (ICVS), School of Health Science, University of Minho; Serviço de Cirurgia Vascular e Centro Académico do Hospital da Senhora da Oliveira Guimarães, Portugal.
Abstract:
CLOVES syndrome is a rare, nonheritable sporadic overgrowth disorder. In the world 130-200 cases have been reported. This is the first case of CLOVES described in Portugal, which had been not been diagnosed for the last 36 years. With this paper, the authors look to highlight the clinical features of this syndrome so that it does not go unrecognized in daily practice. The authors also underline the efficacy and safety of sirolimus, and that this treatment should not be denied, even in adult patients.
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