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Updated: Nov 8, 2025

Comparative Lesions Analysis Through a Targeted Sequencing Approach
Published on: November 5, 2019
Occurrence of two histopathologically different malignancies
Background:
Synchronous primary malignancies are defined as two or more malignancies without finding a subordinate relationship in different organs of the patient. Reports of patients with primary malignancies with hepatocellular carcinoma are rare.
Case:
We describe the course of the disease in a 71-year-old patient with a synchronous occurrence of two histopathologically different malignancies.
Conclusion:
Consistent screening can detect individual tumors early. Understanding the clinicopathological properties and prognostic factors in synchronous malignancies is important to facilitate the treatment.
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